The underlying science is outdated, and there’s a lot of room for advancement, and that’s exactly what we do

Biologica has developed a product with the highest amount of non-recombinant BMP-2, 4, 6, 7, 9 along with the highest levels of non-recombinant PDGF-BB, VEGF, TBFβ-1, IGF-1, and HGF available on the market, available individually or in combination. ProteiOS is purified and packaged under nitrogen gas, and terminally irradiated where it can be used in the OR to stimulate bone growth in a particular area. Each lot of ProteiOS is tested and must meet minimum requirements for protein content for clinical release. What differentiates ProteiOS from other orthobiologics is that, unlike the other growth factor options available in the market, ProteiOS contains many components required for successful tissue regeneration and negates the need to use products with many side-effects. This has led to the creation of a safer product for stimulating bone growth through implantation.

Functioning as more than just a single growth factor or peptide, ProteiOS contains over 600 proteins, identified by mass spectroscopy and ELISA. When added to a synthetic scaffold, ProteiOS displays high growth factor and peptide binding when measured at 15 minutes and also exhibits a long-term sustained release versus the high initial “burst release” of rhBMP-2. “We are able to remove any immunological components from the tissue itself while providing the only sterile growth factor product available within the orthobiologics space,” says Govil.

Having carved a unique niche for itself by improving patients’ lives and the health care providers’ experience through innovative biologic solutions, Biologica has today has been leading the tissue science evolution. The company’s innovation labs continue to develop novel technologies further advancing options within the orthobiologics market.